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The Diary Of A CEO with Steven Bartlett

Most Replayed Moment: The First Warning Signs Of Insulin Resistance! Check Your Skin For This

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Original episode
PodcastThe Diary Of A CEO with Steven Bartlett
Publisher/creatorDOAC
Published
Shortcast updated

About this episode

What if the first signs of insulin resistance are already visible on your body?

Dr Annette Bosworth, also known as Dr Boz, is a physician and author whose work focuses on metabolic health, insulin resistance and ketogenic nutrition.

In this moment, Dr Boz explains how chronically high insulin can quietly affect the body long before many people recognise there’s a problem. She reveals the surprising physical cues, the differences between men and women, and walks Steve through the 12 step keto continuum - a protocol for lowering high insulin.

Listen to the full episode here!

Spotify: https://g2ul0.app.link/NkamPsZlI5b
Apple: https://g2ul0.app.link/plY8uI1lI5b
Watch the Episodes On YouTube: https://www.youtube.com/c/TheDiaryOfACEO/videos

Dr Boz: https://bozmd.com/

Sponsors - Function Health: https://functionhealth.com/DOAC

Episode summary

This AI-generated Shortcast summary may omit nuance. Use the original episode when context or exact wording matters.

You’re 54, and I want that same energy, sharpness, and articulation when I get there. What should I do now so I’m not declining? For starters, I hadn’t eaten breakfast yet.

That’s fine, but by 54, move more calories earlier. A late bite costs more than a morning bite. First food around four, then cod, salad, pasta late looks like time-restricted eating with the big balloon at night.

After a carb-heavy dinner, insulin can work while you sleep. I see that as inflammatory churn that speeds aging. You don’t want insulin high all night.

Give me the 12-year-old version: what is insulin, and why does it matter for longevity?

Insulin moves sugar from blood into cells. When storage is packed, it fills the liver and turns excess fuel into fat—extra storage for a famine that never arrives. Lower insulin lets the body take the trash out.

So boxed, bagged, barcode foods and carbs make those buckets of insulin? And ketones show up when glucose and insulin come down?

Right. Start with fewer than 20 grams of carbs and ketone strips. Many register ketones within a week and naturally skip a meal around day 10. Then practice 16 hours with a nothing burger—no food—and move the window toward sunrise.

Women I know take longer to reach ketosis. Does permanent keto disrupt health?

Women hold fat differently, but high insulin can show up with PCOS, low vitamin D or estrogen, hair loss, and skin tags. I’ve used ketogenic eating for 15 years; in menopause, my brain and energy need ketones. The goal is flexibility: use ketones and glucose.

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